Teamwork Makes the Dreamwork: Cannabis and the Entourage Effect

Cannabis and the Entourage Effect


According to Frontiers medical journal, “In 1998, Professors Raphael Mechoulam and Shimon Ben-Shabat posited that the endocannabinoid system demonstrated an ‘entourage effect’ in which a variety of ‘inactive’ metabolites and closely related molecules markedly increased the activity of the primary endogenous cannabinoids, anandamide and 2-arachidonoylglycerol.”


Translation please?


As it relates to medical marijuana, studies (even the ones dated all the way to the 90s!) continue to show strong findings for one particular age-old adage: teamwork makes the dreamwork. 


This is often referred to as “the entourage effect,” or whole plant medicine, meaning the plant’s  terpenes (as discussed in our previous blogs) as well as its cannabinoids like THC and CBD come together synergistically in our bodies’ own endocannabinoid system. Since each of them benefits different systems in the body in different ways, when combined, they are said to give way to stronger therapeutic effects than possible on their own.


This is said to be one of the reasons behind various strains having their own unique effects since there are completely different “players” at work. When it’s a one-man show, it’s often referred to as an isolate. For example, CBD Oil. Unless it says “full spectrum” (aka whole plant medicine) you aren’t getting as full an effect that you can be.


Interested in diving deeper? Request an appointment with Kaya Life to see if medical marijuana is right for you!

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